452 Neural networks detect cutaneous basal cell carcinomas in histological sections

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Value of CD10 Expression in Differentiating Cutaneous Basal from Squamous Cell Carcinomas and Basal Cell Carcinoma from Trichoepithelioma

Background: In addition to the well-defined histological criteria for squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), immunohistochemical techniques can be used in difficult cases for their differentiation. As differential diagnosis between trichoepithelioma (TE) and BCC is sometimes difficult for the clinician and the pathologist, CD10 may be a useful marker for definite diagnosi...

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Immunohistochemical expression of CD10 in cutaneous basal and squamous cell carcinomas

 Background: Non-melanoma skin cancer is the most common malignant tumor in humans. The role of ultraviolet radiation is well-known in the pathogenesis of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). CD10 is a zinc-dependent metallopeptidase known as common acute lymphoblastic leukemia antigen (CALLA). Although CD10 expression has been investigated in some cutaneous tu...

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value of cd10 expression in differentiating cutaneous basal from squamous cell carcinomas and basal cell carcinoma from trichoepithelioma

background: in addition to the well-defined histological criteria for squamous cell carcinoma (scc) and basal cell carcinoma (bcc), immunohistochemical techniques can be used in difficult cases for their differentiation. as differential diagnosis between trichoepithelioma (te) and bcc is sometimes difficult for the clinician and the pathologist, cd10 may be a useful marker for definite diagnosi...

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Differential protease expression by cutaneous squamous and basal cell carcinomas.

To assess the postulated role of plasminogen activation in tumor invasion, we have investigated the cellular sites of synthesis for urokinase-type (uPA) and tissue-type (tPA) plasminogen activators and their inhibitors (PAI-1 and PAI-2) in two human cutaneous neoplasia that differ in their metastatic potential. The combined use of zymography on tissue sections and in situ hybridization demonstr...

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immunohistochemical expression of cd10 in cutaneous basal and squamous cell carcinomas

background: non-melanoma skin cancer is the most common malignant tumor in humans. the role of ultraviolet radiation is well-known in the pathogenesis of basal cell carcinoma (bcc) and squamous cell carcinoma (scc). cd10 is a zinc-dependent metallopeptidase known as common acute lymphoblastic leukemia antigen (calla). although cd10 expression has been investigated in some cutaneous tumors, to o...

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ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 2019

ISSN: 0022-202X

DOI: 10.1016/j.jid.2019.07.502